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1

Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir

Iulia Diaconu, Vincenzo Cerullo, Sophie Escutenaire, Anna Kanerva, Gerd J. Bauerschmitz, Ruben Hernandez-Alcoceba, Sari Pesonen, Akseli Hemminki

Journal:

The Journal of Gene Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 341 KB

english, 2010

2

Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice

Julien Crettaz, Pedro Berraondo, Itsaso Mauleón, Laura Ochoa, Vijay Shankar, Miguel Barajas, Nico van Rooijen, Stefan Kochanek, Cheng Qian, Jesús Prieto, Rubén Hernández-Alcoceba, Gloria González-Aseg

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 511 KB

english, 2006

3

Lethality in an anti-angiogenic tumor gene therapy model upon constitutive but not inducible expression of the soluble vascular endothelial growth factor receptor 1

Vijayshankar Ganesh Sivanandam, Sam Laurel Stephen, Ruben Hernandez-Alcoceba, Pilar Alzuguren, Maider Zabala, Nico van Rooijen, Cheng Qian, Irina Berger, Marie-Luise Gross, Jesus Prieto, Stefan Kochan

Journal:

The Journal of Gene Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 283 KB

english, 2008

4

Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectors

Pelagia Foka, Aldo Pourchet, Ruben Hernandez-Alcoceba, Polyxeni P. Doumba, George Pissas, Vlassis Kouvatsis, Georgia Dalagiorgou, Dorothea Kazazi, Peggy Marconi, Mariagiovanna Foschini, Roberto Manser

Journal:

The Journal of Gene Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 466 KB

english, 2010

5

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

Joaquı́n Campos, Marı́a del Carmen Núñez, Vicente Rodrı́guez, Antonio Entrena, Rubén Hernández-Alcoceba, Félix Fernández, Juan Carlos Lacal, Miguel A Gallo, Antonio Espinosa

Journal:

European Journal of Medicinal Chemistry

Année:

2001

Langue:

english

Fichier:

PDF, 135 KB

english, 2001

6

Gene therapy strategies for the treatment of cancer. A review

Rubén Hernández-Alcoceba

Journal:

Clinical and Translational Oncology

Année:

2000

Langue:

english

Fichier:

PDF, 469 KB

english, 2000

7

Recent advances in oncolytic virus design

Rubén Hernández-Alcoceba

Journal:

Clinical and Translational Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 185 KB

english, 2011

8

Evaluation of a new dual-specificity promoter for selective induction of apoptosis in breast cancer cells

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Nunez, Gabriel, Clarke, Michael F

Journal:

Cancer Gene Therapy

Année:

2001

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2001

9

Choline kinase inhibitors as a novel approach for antiproliferative drug design

Hernández-Alcoceba, Rubén, Saniger, Luisa, Campos, Joaquín, Núñez, M Carmen, Khaless, Fouad, Gallo, Miguel Angel, Espinosa, Antonio, Lacal, Juan Carlos

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 605 KB

english, 1997

10

Rho proteins induce metastatic properties in vivo

Peso, Luis del, Hernández-Alcoceba, Rubén, Embade, Nieves, Carnero, Amancio, Esteve, Pilar, Paje, Carmen, Lacal, Juan Carlos

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1997

11

Modulation of phospholipase D by hexadecylphosphorylcholine: a putative novel mechanism for its antitumoral activity

Lucas, Luisa, Hernández-Alcoceba, Rubén, Penalva, Verónica, Lacal, Juan Carlos

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 181 KB

english, 2001

12

Evaluation of hepatocellular carcinoma models for preclinical studies

M. Gabriela Kramer, Ruben Hernandez-Alcoceba, Cheng Qian, Jesus Prieto

Journal:

Drug Discovery Today: Disease Models

Année:

2005

Langue:

english

Fichier:

PDF, 269 KB

english, 2005

13

Prolonged and inducible transgene expression in the liver using gutless adenovirus: A potential therapy for liver cancer

Lin Wang, RubÉN. HernÁndez-Alcoceba, Vijay Shankar, Maider Zabala, Stefan Kochanek, Bruno Sangro, M.Gabriela Kramer, Jesus Prieto, Cheng Qian

Journal:

Gastroenterology

Année:

2004

Langue:

english

Fichier:

PDF, 573 KB

english, 2004

14

Gene therapy of liver diseases

Prieto, Jesus, Qian, Cheng, Hernandez-Alcoceba, Ruben, Gonzalez-Aseguinolaza, Gloria, Mazzolini, Guillermo, Sangro, Bruno, Kramer, M Gabriela

Journal:

Expert Opinion on Biological Therapy

Année:

2004

Langue:

english

Fichier:

PDF, 262 KB

english, 2004

15

New Oncolytic Adenoviruses with Hypoxia- and Estrogen Receptor-Regulated Replication

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Qian, Dalong, Clarke, Michael F.

Journal:

Human Gene Therapy

Année:

2002

Langue:

english

Fichier:

PDF, 350 KB

english, 2002

16

A Novel, Conditionally Replicative Adenovirus for the Treatment of Breast Cancer That Allows Controlled Replication of E1a-Deleted Adenoviral Vectors

Hernandez-Alcoceba, Ruben, Pihalja, Michael, Wicha, Max S., Clarke, Michael F.

Journal:

Human Gene Therapy

Année:

2000

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2000

17

Human Adenovirus Replicates in Immunocompetent Models of Pancreatic Cancer in Syrian Hamsters

Bortolanza, Sergia, Alzuguren, Pilar, Buñuales, Maria, Qian, Cheng, Prieto, Jesus, Hernandez-Alcoceba, Ruben

Journal:

Human Gene Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 488 KB

english, 2007

18

274. Antitumor Effect of Controlled Expression of Interleukin-12 in a Murine Model of Liver Metastases

Mauleon, Itsaso, Crettaz, Julien, Gonzalez-Aseguinolaza, Gloria, Zabala, Maider, Kramer, Gabriela, Kochanek, Stephan, Prieto, Jesus, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 83 KB

english, 2006

19

652. In Vivo Evaluation of an Oncolytic Adenovirus Regulated by Hypoxia

Bortolanza, Sergia, Prieto, Jesus, Alzuguren, Pilar, Carro, Elvira, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 82 KB

english, 2006

20

Treatment of Pancreatic Cancer With an Oncolytic Adenovirus Expressing Interleukin-12 in Syrian Hamsters

Bortolanza, Sergia, Bunuales, Maria, Otano, Itziar, Gonzalez-Aseguinolaza, Gloria, Ortiz-de-Solorzano, Carlos, Perez, Daniel, Prieto, Jesus, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2009

21

Cytokines for the treatment of gastrointestinal cancers: clinical experience and new perspectives

Hernandez-Alcoceba, Ruben, Sangro, Bruno, Berraondo, Pedro, Gonzalez-Aseguinolaza, Gloria, Prieto, Jesus

Journal:

Expert Opinion on Investigational Drugs

Année:

2013

Langue:

english

Fichier:

PDF, 661 KB

english, 2013

22

Immunochemotherapy against colon cancer by gene transfer of interleukin-12 in combination with oxaliplatin

Hernandez-Alcoceba, Ruben, Berraondo, Pedro

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2012

23

Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12

Hernandez-Alcoceba, Ruben, Poutou, Joanna, Ballesteros-Briones, María Cristina, Smerdou, Cristian

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2016

24

164. Improvement of Gene Therapy for Wilson Disease

Murillo, Oihana, Moreno, Daniel, Gazquez, Cristina, Navarro-Blasco, Iñigo, Prieto, Jesus, Hernandez-Alcoceba, Ruben, Gonzalez-Aseguinolaza, Gloria

Journal:

Molecular Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 269 KB

english, 2016

25

110. Safety and Antitumor Effect of Oncolytic and Helper-Dependent Adenoviruses Expressing Interleukin-12 Variants in a Hamster Pancreatic Cancer Model

Poutou, Joanna, Bunuales, Maria, Gonzalez, Manuela, Garcia-Aragoncillo, Eva, Quetglas, Jose I., Casado, Raquel, Bravo-Perez, Carlos, Alzuguren, Pilar, Hernandez-Alcoceba, Ruben

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 298 KB

english, 2015

26

702. Long Term Metabolic Correction of Wilson Disease

Murillo, Oihana, Moreno-Luqui, Daniel, Gazquez, Cristina, Martínez-Espartosa, Debora, Monreal, Ignacio, Guembe, Laura, Moreno, Armando, Corrales, Fernando, Prieto, Jesús, Hernández-Alcoceba, Ruben, Go

Journal:

Molecular Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 272 KB

english, 2015

27

Improvement of Adeno-Associated Virus-Mediated Liver Transduction Efficacy by Regional Administration in Macaca fascicularis

Zabaleta, Nerea, Salas, David, Paramo, Maria, Hommel, Mirja, Sier-Ferreira, Valerie, Hernandez-Alcoceba, Ruben, Prieto, Jesus, Bilbao, Jose I., Gonzalez-Aseguinolaza, Gloria

Journal:

Human Gene Therapy Clinical Development

Année:

2017

Langue:

english

Fichier:

PDF, 999 KB

english, 2017

28

Adaptation of vectors and drug-inducible systems for controlled expression of transgenes in the tumor microenvironment

Poutou, Joanna, Bunuales, Maria, Gonzalez-Aparicio, Manuela, German, Beatriz, Zugasti, Ines, Hernandez-Alcoceba, Ruben

Journal:

Journal of Controlled Release

Année:

2017

Langue:

english

Fichier:

PDF, 2.09 MB

english, 2017

29

Visualization of the therapeutic efficacy of a gene correction approach in Wilson's disease by Laser-ablation inductively coupled mass spectrometry

Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernandez-Alcoceba, Ruben, Uerlings, Ricarda, Gonzalez-Aseguinolaza, Gloria, Weiskirchen, Ralf

Journal:

Journal of Hepatology

Année:

2018

Langue:

english

Fichier:

PDF, 2.54 MB

english, 2018

30

Brain copper storage after genetic long-term correction in a mouse model of Wilson disease

Uerlings, Ricarda, Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernández-Alcoceba, Rubén, González-Aseguinolaza, Gloria, Weiskirchen, Ralf

Journal:

Neurology: Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 640 KB

english, 2018

31

Gene therapy of liver cancer

Hernandez-Alcoceba, Ruben

Journal:

World Journal of Gastroenterology

Année:

2006

Langue:

english

Fichier:

PDF, 715 KB

english, 2006

32

Inhibition of adenovirus infection by mifepristone

Marrugal-Lorenzo, José A., Serna-Gallego, Ana, González-González, Loreto, Buñuales, Maria, Poutou, Joanna, Pachón, Jerónimo, Gonzalez-Aparicio, Manuela, Hernandez-Alcoceba, Ruben, Sánchez-Céspedes, Ja

Journal:

Antiviral Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2018

33

Gene therapy of liver cancer

Hernández-Alcoceba, Rubén, Sangro, Bruno, Prieto, Jesús

Journal:

Annals of Hepatology

Année:

2007

Langue:

english

Fichier:

PDF, 98 KB

english, 2007